Matthew Spite, Ph.D.
Matthew Spite, Ph.D.
Harvard Medical School and Brigham and Women's Hospital
Verified email at - Homepage
Cited by
Cited by
Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions
CN Serhan, R Yang, K Martinod, K Kasuga, PS Pillai, TF Porter, SF Oh, ...
Journal of Experimental Medicine 206 (1), 15-23, 2009
Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
M Spite, LV Norling, L Summers, R Yang, D Cooper, NA Petasis, ...
Nature 461 (7268), 1287-1291, 2009
Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases
M Spite, J Claria, CN Serhan
Cell metabolism 19 (1), 21-36, 2014
Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins
M Spite, CN Serhan
Circulation research 107 (10), 1170-1184, 2010
An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques
G Fredman, J Hellmann, JD Proto, G Kuriakose, RA Colas, B Dorweiler, ...
Nature communications 7 (1), 12859, 2016
Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice
J Hellmann, Y Tang, M Kosuri, A Bhatnagar, M Spite
The FASEB journal 25 (7), 2399, 2011
Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis
KJ Ho, M Spite, CD Owens, H Lancero, AHK Kroemer, R Pande, ...
The American journal of pathology 177 (4), 2116-2123, 2010
Resolution of acute inflammation and the role of resolvins in immunity, thrombosis, and vascular biology
BE Sansbury, M Spite
Circulation research 119 (1), 113-130, 2016
Proresolution therapy for the treatment of delayed healing of diabetic wounds
Y Tang, MJ Zhang, J Hellmann, M Kosuri, A Bhatnagar, M Spite
Diabetes 62 (2), 618-627, 2013
Cutting edge: humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing
LV Norling, M Spite, R Yang, RJ Flower, M Perretti, CN Serhan
The Journal of Immunology 186 (10), 5543-5547, 2011
Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway
G Fredman, L Ozcan, S Spolitu, J Hellmann, M Spite, J Backs, I Tabas
Proceedings of the National Academy of Sciences 111 (40), 14530-14535, 2014
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis
B Cai, EB Thorp, AC Doran, BE Sansbury, MJAP Daemen, B Dorweiler, ...
The Journal of clinical investigation 127 (2), 564-568, 2017
Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids
MJ Zhang, M Spite
Annual review of nutrition 32, 203-227, 2012
Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity
M Spite, J Hellmann, Y Tang, SP Mathis, M Kosuri, A Bhatnagar, VR Jala, ...
The Journal of Immunology 187 (4), 1942-1949, 2011
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
B Cai, EB Thorp, AC Doran, M Subramanian, BE Sansbury, CS Lin, ...
Proceedings of the National Academy of Sciences 113 (23), 6526-6531, 2016
Metabolic remodeling of white adipose tissue in obesity
TD Cummins, CR Holden, BE Sansbury, AA Gibb, J Shah, N Zafar, ...
American Journal of Physiology-Endocrinology and Metabolism 307 (3), E262-E277, 2014
Regulatory T cells license macrophage pro-resolving functions during atherosclerosis regression
M Sharma, MP Schlegel, MS Afonso, EJ Brown, K Rahman, A Weinstock, ...
Circulation research 127 (3), 335-353, 2020
Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
BE Sansbury, TD Cummins, Y Tang, J Hellmann, CR Holden, ...
Circulation research 111 (9), 1176-1189, 2012
12-Lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat
LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, ...
Cell metabolism 30 (4), 768-783. e7, 2019
Macrophage PPARγ, a lipid activated transcription factor controls the growth factor GDF3 and skeletal muscle regeneration
T Varga, R Mounier, A Patsalos, P Gogolák, M Peloquin, A Horvath, A Pap, ...
Immunity 45 (5), 1038-1051, 2016
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