Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls 1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ... Nature 447 (7145), 661-678, 2007 | 9461 | 2007 |
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1444 | 2007 |
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ... Nature 450 (7171), 887-892, 2007 | 710 | 2007 |
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation M Xue, N Rabbani, H Momiji, P Imbasi, MM Anwar, N Kitteringham, ... Biochemical Journal 443 (1), 213-222, 2012 | 310 | 2012 |
Activation of NF-E2–related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease M Xue, Q Qian, A Adaikalakoteswari, N Rabbani, R Babaei-Jadidi, ... Diabetes 57 (10), 2809-2817, 2008 | 285 | 2008 |
Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation M Xue, MO Weickert, S Qureshi, NB Kandala, A Anwar, M Waldron, ... Diabetes 65 (8), 2282-2294, 2016 | 218 | 2016 |
Glyoxalase in ageing M Xue, N Rabbani, PJ Thornalley Seminars in cell & developmental biology 22 (3), 293-301, 2011 | 208 | 2011 |
Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes N Rabbani, L Godfrey, M Xue, F Shaheen, M Geoffrion, R Milne, ... Diabetes 60 (7), 1973-1980, 2011 | 184 | 2011 |
Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics N Rabbani, M Xue, PJ Thornalley Glycoconjugate journal 33, 513-525, 2016 | 180 | 2016 |
Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments N Rabbani, M Xue, PJ Thornalley Clinical science 130 (19), 1677-1696, 2016 | 163 | 2016 |
Activity, regulation, copy number and function in the glyoxalase system N Rabbani, M Xue, PJ Thornalley Biochemical Society transactions 42 (2), 419-424, 2014 | 113 | 2014 |
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal Z Irshad, M Xue, A Ashour, JR Larkin, PJ Thornalley, N Rabbani Scientific reports 9 (1), 7889, 2019 | 104 | 2019 |
Frequency modulated translocational oscillations of Nrf2 mediate the antioxidant response element cytoprotective transcriptional response M Xue, H Momiji, N Rabbani, G Barker, T Bretschneider, A Shmygol, ... Antioxidants & redox signaling 23 (7), 613-629, 2015 | 83 | 2015 |
Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology—Involvement in tumour suppression, tumour growth, multidrug resistance and … N Rabbani, M Xue, MO Weickert, PJ Thornalley Seminars in Cancer Biology 49, 83-93, 2018 | 68 | 2018 |
Dicarbonyl stress, protein glycation and the unfolded protein response N Rabbani, M Xue, PJ Thornalley Glycoconjugate Journal 38 (3), 331-340, 2021 | 57 | 2021 |
Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure … N Rabbani, M Xue, MO Weickert, PJ Thornalley Nutrients 13 (7), 2374, 2021 | 53 | 2021 |
Vulnerabilities of the SARS-CoV-2 virus to proteotoxicity—opportunity for repurposed chemotherapy of COVID-19 infection MS Al-Motawa, H Abbas, P Wijten, A De la Fuente, M Xue, N Rabbani, ... Frontiers in pharmacology 11, 585408, 2020 | 50 | 2020 |
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity F Zhang, J Masania, A Anwar, M Xue, D Zehnder, H Kanji, N Rabbani, ... Kidney international 90 (2), 396-403, 2016 | 42 | 2016 |
Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension C Wallace, MZ Xue, SJ Newhouse, ACB Marçano, AK Onipinla, B Burke, ... The American Journal of Human Genetics 79 (2), 323-331, 2006 | 37 | 2006 |
Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study PB Munroe, C Wallace, MZ Xue, ACB Marçano, RJ Dobson, AK Onipinla, ... Hypertension 48 (1), 105-111, 2006 | 37 | 2006 |