フォロー
Derek Narendra, MD, PhD
Derek Narendra, MD, PhD
Lasker Clinical Research Scholar and Tenure Track Investigator, NINDS, NIH
確認したメール アドレス: nih.gov
タイトル
引用先
引用先
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13477*2021
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
D Narendra, A Tanaka, DF Suen, RJ Youle
The Journal of cell biology 183 (5), 795-803, 2008
41662008
Mechanisms of mitophagy
RJ Youle, DP Narendra
Nature reviews Molecular cell biology 12 (1), 9-14, 2011
34232011
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
DP Narendra, SM Jin, A Tanaka, DF Suen, CA Gautier, J Shen, ...
PLoS biology 8 (1), e1000298, 2010
29702010
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ...
The Lancet Neurology 18 (12), 1091-1102, 2019
15582019
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
A Tanaka, MM Cleland, S Xu, DP Narendra, DF Suen, M Karbowski, ...
Journal of Cell Biology 191 (7), 1367-1380, 2010
14412010
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle
Journal of Cell Biology 191 (5), 933-942, 2010
13712010
Parkin and PINK1 mitigate STING-induced inflammation
DA Sliter, J Martinez, L Hao, XI Chen, N Sun, TD Fischer, JL Burman, Y Li, ...
Nature 561 (7722), 258-262, 2018
10412018
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
D Narendra, LA Kane, DN Hauser, IM Fearnley, RJ Youle
Autophagy 6 (8), 1090-1106, 2010
8422010
Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control
DP Narendra, RJ Youle
Antioxidants & redox signaling 14 (10), 1929-1938, 2011
4062011
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
DF Suen, DP Narendra, A Tanaka, G Manfredi, RJ Youle
Proceedings of the National Academy of Sciences 107 (26), 11835-11840, 2010
3652010
Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism
D Narendra, JE Walker, R Youle
Cold Spring Harbor perspectives in biology 4 (11), a011338, 2012
3492012
Mitochondrial dysfunction and mitophagy in Parkinson’s disease: from mechanism to therapy
AB Malpartida, M Williamson, DP Narendra, R Wade-Martins, BJ Ryan
Trends in biochemical sciences 46 (4), 329-343, 2021
3072021
Parkin-induced mitophagy in the pathogenesis of Parkinson disease
D Narendra, A Tanaka, DF Suen, RJ Youle
Autophagy 5 (5), 706-708, 2009
2712009
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
M Lazarou, DP Narendra, SM Jin, E Tekle, S Banerjee, RJ Youle
Journal of Cell Biology 200 (2), 163-172, 2013
2502013
When patients lack capacity: the roles that patients with terminal diagnoses would choose for their physicians and loved ones in making medical decisions
MT Nolan, M Hughes, DP Narendra, JR Sood, PB Terry, AB Astrow, J Kub, ...
Journal of pain and symptom management 30 (4), 342-353, 2005
1112005
Penetrance of Parkinson's Disease in LRRK2 p.G2019S Carriers Is Modified by a Polygenic Risk Score
H Iwaki, C Blauwendraat, MB Makarious, S Bandrés‐Ciga, HL Leonard, ...
Movement Disorders 35 (5), 774-780, 2020
612020
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
X Huang, BP Wu, D Nguyen, YT Liu, M Marani, J Hench, P Bénit, ...
Human molecular genetics 27 (22), 3881-3900, 2018
592018
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
YT Liu, X Huang, D Nguyen, MK Shammas, BP Wu, E Dombi, ...
Human Molecular Genetics 29 (9), 1547-1567, 2020
562020
Investigation of autosomal genetic sex differences in Parkinson's disease
C Blauwendraat, H Iwaki, MB Makarious, S Bandres‐Ciga, HL Leonard, ...
Annals of neurology 90 (1), 35-42, 2021
432021
現在システムで処理を実行できません。しばらくしてからもう一度お試しください。
論文 1–20