| SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer G Li, W Ci, S Karmakar, K Chen, R Dhar, Z Fan, Z Guo, J Zhang, Y Ke, ... Cancer cell 25 (4), 455-468, 2014 | 177 | 2014 |
| Dual RING E3 architectures regulate multiubiquitination and ubiquitin chain elongation by APC/C NG Brown, R VanderLinden, ER Watson, F Weissmann, A Ordureau, ... Cell 165 (6), 1440-1453, 2016 | 147 | 2016 |
| Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly NG Brown, ER Watson, F Weissmann, MA Jarvis, R VanderLinden, ... Molecular cell 56 (2), 246-260, 2014 | 113 | 2014 |
| Posing the APC/C E3 ubiquitin ligase to orchestrate cell division ER Watson, NG Brown, JM Peters, H Stark, BA Schulman Trends in cell biology 29 (2), 117-134, 2019 | 106 | 2019 |
| Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown JJ Frye, NG Brown, G Petzold, ER Watson, CRR Grace, A Nourse, ... Nature structural & molecular biology 20 (7), 827-835, 2013 | 104 | 2013 |
| RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex NG Brown, R VanderLinden, ER Watson, R Qiao, CRR Grace, ... Proceedings of the National Academy of Sciences 112 (17), 5272-5279, 2015 | 93 | 2015 |
| Gene expression and cell identity controlled by anaphase-promoting complex E Oh, KG Mark, A Mocciaro, ER Watson, JR Prabu, DD Cha, ... Nature 579 (7797), 136-140, 2020 | 81 | 2020 |
| Multiple weak linear motifs enhance recruitment and processivity in SPOP-mediated substrate ubiquitination WK Pierce, CR Grace, J Lee, A Nourse, MR Marzahn, ER Watson, ... Journal of molecular biology 428 (6), 1256-1271, 2016 | 54 | 2016 |
| Molecular glue CELMoD compounds are regulators of cereblon conformation ER Watson, S Novick, ME Matyskiela, PP Chamberlain, A H. de la Peña, ... Science 378 (6619), 549-553, 2022 | 51 | 2022 |
| Structures of the human LONP1 protease reveal regulatory steps involved in protease activation M Shin, ER Watson, AS Song, JT Mindrebo, SJ Novick, PR Griffin, ... Nature communications 12 (1), 3239, 2021 | 43 | 2021 |
| Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site ER Watson, CRR Grace, W Zhang, DJ Miller, IF Davidson, JR Prabu, S Yu, ... Proceedings of the National Academy of Sciences 116 (35), 17280-17289, 2019 | 27 | 2019 |
| Complex interactions of Tyrp1 in the eye H Lu, L Li, ER Watson, RW Williams, EE Geisert, MM Jablonski, L Lu Molecular vision 17, 2455, 2011 | 24 | 2011 |
| Measuring APC/C-dependent ubiquitylation in vitro MA Jarvis, NG Brown, ER Watson, R VanderLinden, BA Schulman, ... Cell Cycle Oscillators: Methods and Protocols, 287-303, 2016 | 14 | 2016 |
| H. de la Pena ER Watson, S Novick, ME Matyskiela, PP Chamberlain A., Zhu, J., Tran, E., Griffin, PR, Wertz, IE, and Lander, GC, 549-553, 2022 | 11 | 2022 |
| APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain CJ Ferguson, O Urso, T Bodrug, BM Gassaway, ER Watson, JR Prabu, ... Molecular cell 82 (1), 90-105. e13, 2022 | 4 | 2022 |
| APC/C-dependent control of gene expression and cell identity E Oh, KG Mark, A Mocciaro, ER Watson, JR Prabu, DD Cha, ... Nature 579 (7797), 136, 2020 | 3 | 2020 |
| Allosteric differences dictate GroEL complementation of E. coli J Sivinski, D Ngo, CJ Zerio, AJ Ambrose, ER Watson, LK Kaneko, ... FASEB journal: official publication of the Federation of American Societies …, 2022 | 1 | 2022 |
| A Protein Engineering Approach for Uncovering Cryptic Ubiquitin-binding Sites: from a Ubiquitin-Variant Inhibitor of APC/C to K48 Chain Binding ER Watson, CRR Grace, W Zhang, DJ Miller, IF Davidson, JR Prabu, S Yu, ... bioRxiv, 669846, 2019 | | 2019 |
| Understanding Structural And Functional Mechanisms of Emi1 Inhibition of the Anaphase Promoting Complex ER Watson | | 2016 |
