Luis Zapata

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Stephan OssowskiInstitute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, GermanyVerified email at crg.eu
Andrea SottorivaHuman TechnopoleVerified email at fht.org
Trevor A GrahamDirector, Centre for Evolution and Cancer, ICR, LondonVerified email at icr.ac.uk
Benjamin WernerReader, Barts Cancer Institute, Queen Mary University LondonVerified email at qmul.ac.uk
Marc J WilliamsMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Chris P BarnesUniversity College LondonVerified email at ucl.ac.uk
Xavier Estivill MD PhDqGenomics (Quantitative Genomics Laboratories)Verified email at qgenomics.com
Giulio CaravagnaCancer Data Science Laboratory, University of TriesteVerified email at units.it
Khalid AbdulJabbarInstitute of Cancer Research, London, UKVerified email at icr.ac.uk
Korbinian SchneebergerLudwig-Maximilians-University Munich (LMU); Max Planck Institute for Plant Breeding ResearchVerified email at lmu.de
Geo Velikkakam JamesTeam Leader Bioinformatics, Rijk Zwaan R&D FijnaartVerified email at rijkzwaan.nl
William CrossResearcher, Lecturer, University of WestminsterVerified email at westminster.ac.uk
Daniela BezdanVerified email at med.uni-tuebingen.de
Daniel NicholEvolutionary Genomics and Modelling, Institute of Cancer Research, UKVerified email at icr.ac.uk
Dr George D CresswellSt. Anna Children's Cancer Research InstituteVerified email at ccri.at
Matthias WillmannInstitute of Medicial Microbiology and Hygiene, University of Tuebingen, GermanyVerified email at med.uni-tuebingen.de
Cristian Tornador, Tornador CPhD in Biomedicine - Bioinformatic, Universitat Pompeu FabraVerified email at upf.edu
Pedro G. FerreiraDepartment of Computer Science, Faculty of Sciences University of Porto; INESC-TECVerified email at fc.up.pt
Laia BassaganyasPostdoctoral Researcher - IGF MontpellierVerified email at igf.cnrs.fr
Alejandro MaassCenter for Mathematical Modeling, University of ChileVerified email at dim.uchile.cl

Luis Zapata

Other namesLuis Zapata Ortiz

Team Leader, Center For Evolution And Cancer, ICR

Verified email at icr.ac.uk

Genomics Bioinformatics Evolutionary Biology Cancer


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Geospatial immune variability illuminates differential evolution of lung adenocarcinoma K AbdulJabbar, SEA Raza, R Rosenthal, M Jamal-Hanjani, S Veeriah, ... Nature medicine 26 (7), 1054-1062, 2020	239	2020
The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana E Wijnker, G Velikkakam James, J Ding, F Becker, JR Klasen, V Rawat, ... Elife 2, e01426, 2013	228	2013
Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms L Zapata, J Ding, EM Willing, B Hartwig, D Bezdan, WB Jiao, V Patel, ... Proceedings of the National Academy of Sciences 113 (28), E4052-E4060, 2016	208	2016
Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature genetics 52 (9), 898-907, 2020	104	2020
Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome L Zapata, O Pich, L Serrano, FA Kondrashov, S Ossowski, MH Schaefer Genome biology 19, 1-17, 2018	103	2018
Evolutionary dynamics of neoantigens in growing tumors E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, L Zapata, ... Nature genetics 52 (10), 1057-1066, 2020	95	2020
Identification of gene mutations and fusion genes in patients with Sézary syndrome A Prasad, R Rabionet, B Espinet, L Zapata, A Puiggros, C Melero, A Puig, ... Journal of Investigative Dermatology 136 (7), 1490-1499, 2016	93	2016
Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022	84	2022
Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study M Willmann, D Bezdan, L Zapata, H Susak, W Vogel, K Schröppel, J Liese, ... Journal of Antimicrobial Chemotherapy 70 (5), 1322-1330, 2015	70	2015
The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022	61	2022
Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis L Bassaganyas, S Beà, G Escaramis, C Tornador, I Salaverria, L Zapata, ... Leukemia 27 (12), 2376-2379, 2013	47	2013
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking GD Cresswell, D Nichol, I Spiteri, H Tari, L Zapata, T Heide, CC Maley, ... Nature communications 11 (1), 1446, 2020	43	2020
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios MJ Williams, L Zapata, B Werner, CP Barnes, A Sottoriva, TA Graham Elife 9, e48714, 2020	39	2020
Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution E Hénaff, L Zapata, JM Casacuberta, S Ossowski BMC genomics 16, 1-16, 2015	39	2015
SalmonDB: a bioinformatics resource for Salmo salar and Oncorhynchus mykiss A Di Genova, A Aravena, L Zapata, M Gonzalez, A Maass, P Iturra Database 2011, bar050, 2011	39	2011
The rate and spectrum of mosaic mutations during embryogenesis revealed by RNA sequencing of 49 tissues F Muyas, L Zapata, R Guigó, S Ossowski Genome Medicine 12, 1-14, 2020	33	2020
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors L Zapata, G Caravagna, MJ Williams, E Lakatos, K AbdulJabbar, ... Nature Genetics 55 (3), 451-460, 2023	32*	2023
Reply to ‘Neutral tumor evolution?’ T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ... Nature genetics 50 (12), 1633-1637, 2018	32	2018
Allele balance bias identifies systematic genotyping errors and false disease associations F Muyas, M Bosio, A Puig, H Susak, L Domènech, G Escaramis, L Zapata, ... Human mutation 40 (1), 115-126, 2019	31	2019
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells M Tarbier, SD Mackowiak, J Frade, S Catuara-Solarz, I Biryukova, ... Nature communications 11 (1), 5445, 2020	29*	2020

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