The role of apolipoprotein E in Alzheimer's disease J Kim, JM Basak, DM Holtzman Neuron 63 (3), 287-303, 2009 | 1897 | 2009 |
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ... Science translational medicine 3 (89), 89ra57-89ra57, 2011 | 1389 | 2011 |
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation L Petrucelli, D Dickson, K Kehoe, J Taylor, H Snyder, A Grover, ... Human molecular genetics 13 (7), 703-714, 2004 | 820 | 2004 |
Aβ42 is essential for parenchymal and vascular amyloid deposition in mice E McGowan, F Pickford, J Kim, L Onstead, J Eriksen, C Yu, L Skipper, ... Neuron 47 (2), 191-199, 2005 | 715 | 2005 |
Aβ40 inhibits amyloid deposition in vivo J Kim, L Onstead, S Randle, R Price, L Smithson, C Zwizinski, ... Journal of Neuroscience 27 (3), 627-633, 2007 | 467 | 2007 |
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease SE Wahrle, H Jiang, M Parsadanian, J Kim, A Li, A Knoten, S Jain, ... The Journal of clinical investigation 118 (2), 671-682, 2008 | 444 | 2008 |
Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans JR Cirrito, BM Disabato, JL Restivo, DK Verges, WD Goebel, A Sathyan, ... Proceedings of the National Academy of Sciences 108 (36), 14968-14973, 2011 | 358 | 2011 |
Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice AW Kraft, X Hu, H Yoon, P Yan, Q Xiao, Y Wang, SC Gil, J Brown, ... The FASEB Journal 27 (1), 187, 2013 | 316 | 2013 |
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ... Journal of Biological Chemistry 287 (50), 41774-41786, 2012 | 281 | 2012 |
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular Aβ clearance J Kim, JM Castellano, H Jiang, JM Basak, M Parsadanian, V Pham, ... Neuron 64 (5), 632-644, 2009 | 279 | 2009 |
Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144 CM Ramírez, N Rotllan, AV Vlassov, A Dávalos, M Li, L Goedeke, ... Circulation research 112 (12), 1592-1601, 2013 | 244 | 2013 |
miR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression J Kim, H Yoon, CM Ramírez, SM Lee, HS Hoe, C Fernández-Hernando, ... Experimental neurology 235 (2), 476-483, 2012 | 228 | 2012 |
Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ42 Peptide AK Sharma, ST Pavlova, J Kim, D Finkelstein, NJ Hawco, NP Rath, J Kim, ... Journal of the American Chemical Society 134 (15), 6625-6636, 2012 | 224 | 2012 |
Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes JM Basak, PB Verghese, H Yoon, J Kim, DM Holtzman Journal of Biological Chemistry 287 (17), 13959-13971, 2012 | 212 | 2012 |
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy Nature communications 6, 7247, 2015 | 202* | 2015 |
Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis J Kim, H Jiang, S Park, AEM Eltorai, FR Stewart, H Yoon, JM Basak, ... Journal of Neuroscience 31 (49), 18007-18012, 2011 | 202 | 2011 |
Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease F Liao, H Yoon, J Kim Current opinion in lipidology 28 (1), 60-67, 2017 | 179 | 2017 |
Apolipoprotein E in synaptic plasticity and Alzheimer’s disease: potential cellular and molecular mechanisms J Kim, H Yoon, J Basak, J Kim Molecules and cells 37 (11), 767-776, 2014 | 150 | 2014 |
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis J Kim, AEM Eltorai, H Jiang, F Liao, PB Verghese, J Kim, FR Stewart, ... Journal of Experimental Medicine 209 (12), 2149-2156, 2012 | 147 | 2012 |
Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease YM Sung, T Lee, H Yoon, AM DiBattista, JM Song, Y Sohn, EI Moffat, ... Experimental neurology 239, 192-201, 2013 | 144 | 2013 |