| Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis S Kato, SY Han, W Liu, K Otsuka, H Shibata, R Kanamaru, C Ishioka Proceedings of the National Academy of Sciences 100 (14), 8424-8429, 2003 | 917 | 2003 |
| Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene H Shibata, K Toyama, H Shioya, M Ito, M Hirota, S Hasegawa, ... Science 278 (5335), 120-123, 1997 | 686 | 1997 |
| Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer H Ohori, H Yamakoshi, M Tomizawa, M Shibuya, Y Kakudo, A Takahashi, ... Molecular cancer therapeutics 5 (10), 2563-2571, 2006 | 290 | 2006 |
| A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients M Kanai, Y Otsuka, K Otsuka, M Sato, T Nishimura, Y Mori, M Kawaguchi, ... Cancer chemotherapy and pharmacology 71 (6), 1521-1530, 2013 | 223 | 2013 |
| Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae H Shimodaira, N Filosi, H Shibata, T Suzuki, P Radice, R Kanamaru, ... Nature genetics 19 (4), 384-389, 1998 | 198 | 1998 |
| Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay SY Han, H Kato, S Kato, T Suzuki, H Shibata, S Ishii, K Shiiba, S Matsuno, ... Cancer research 60 (12), 3147-3151, 2000 | 193 | 2000 |
| Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030 L Lin, Y Liu, H Li, PK Li, J Fuchs, H Shibata, Y Iwabuchi, J Lin British journal of cancer 105 (2), 212-220, 2011 | 180 | 2011 |
| Functional evaluation of p53 and PTEN gene mutations in gliomas H Kato, S Kato, T Kumabe, Y Sonoda, T Yoshimoto, S Kato, SY Han, ... Clinical Cancer Research 6 (10), 3937-3943, 2000 | 125 | 2000 |
| Lack of correlation between p53-dependent transcriptional activity and the ability to induce apoptosis among 179 mutant p53s Y Kakudo, H Shibata, K Otsuka, S Kato, C Ishioka Cancer research 65 (6), 2108-2114, 2005 | 116 | 2005 |
| Structure–activity relationship of C< sub> 5</sub>-curcuminoids and synthesis of their molecular probes thereof H Yamakoshi, H Ohori, C Kudo, A Sato, N Kanoh, C Ishioka, H Shibata, ... Bioorganic & medicinal chemistry 18 (3), 1083-1092, 2010 | 96 | 2010 |
| Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas B Hutzen, L Friedman, M Sobo, L Lin, L Cen, S De Angelis, H Yamakoshi, ... International journal of oncology 35 (4), 867-872, 2009 | 95 | 2009 |
| A new combination chemotherapy with cis-diammine-glycolatoplatinum (Nedaplatin) and 5-fluorouracil for advanced esophageal cancers. T Yoshioka, M Gamoh, R Shineha, S Ishibashi, H Shibata, T Suzuki, ... Internal medicine (Tokyo, Japan) 38 (11), 844-848, 1999 | 94 | 1999 |
| Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene S Hasegawa, T Sato, H Akazawa, H Okada, A Maeno, M Ito, Y Sugitani, ... Proceedings of the National Academy of Sciences 99 (1), 297-302, 2002 | 81 | 2002 |
| Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo H Shibata, H Yamakoshi, A Sato, H Ohori, Y Kakudo, C Kudo, ... Cancer science 100 (5), 956-960, 2009 | 74 | 2009 |
| Preliminary estimation of the prevalence of chemotherapy-induced dysgeusia in Japanese patients with cancer H Imai, H Soeda, K Komine, K Otsuka, H Shibata BMC palliative care 12 (1), 38, 2013 | 63 | 2013 |
| Synthesis of 86 species of 1, 5-diaryl-3-oxo-1, 4-pentadienes analogs of curcumin can yield a good lead in vivo C Kudo, H Yamakoshi, A Sato, H Nanjo, H Ohori, C Ishioka, Y Iwabuchi, ... BMC pharmacology 11 (1), 4, 2011 | 60 | 2011 |
| Curcumin analog GO‐Y030 is a novel inhibitor of IKKβ that suppresses NF‐κB signaling and induces apoptosis A Sato, C Kudo, H Yamakoshi, Y Uehara, H Ohori, C Ishioka, Y Iwabuchi, ... Cancer science 102 (5), 1045-1051, 2011 | 59 | 2011 |
| Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. RC Gallagher, T Hay, V Meniel, C Naughton, TJ Anderson, H Shibata, ... Oncogene 21 (42), 6446-6457, 2002 | 50 | 2002 |
| Prediction of breast cancer prognosis by gene expression profile of TP53 status S Takahashi, T Moriya, T Ishida, H Shibata, H Sasano, N Ohuchi, ... Cancer science 99 (2), 324-332, 2008 | 48 | 2008 |
| Novel curcumin analogs, GO-Y030 and GO-Y078, are multi-targeted agents with enhanced abilities for multiple myeloma C Kudo, H Yamakoshi, A Sato, H Ohori, C Ishioka, Y Iwabuchi, H Shibata Anticancer research 31 (11), 3719-3726, 2011 | 44 | 2011 |
