Nozomu Kono
Nozomu Kono
Graduate School of Pharmaceutical Sciences, the University of Tokyo
Verified email at
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Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation
K Eguchi, I Manabe, Y Oishi-Tanaka, M Ohsugi, N Kono, F Ogata, N Yagi, ...
Cell metabolism 15 (4), 518-533, 2012
Decrease in membrane phospholipid unsaturation induces unfolded protein response
H Ariyama, N Kono, S Matsuda, T Inoue, H Arai
Journal of Biological Chemistry 285 (29), 22027-22035, 2010
Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains
T Nishimura, N Tamura, N Kono, Y Shimanaka, H Arai, H Yamamoto, ...
The EMBO journal 36 (12), 1719-1735, 2017
Caenorhabditis elegans mboa-7, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol
HC Lee, T Inoue, R Imae, N Kono, S Shirae, S Matsuda, K Gengyo-Ando, ...
Molecular biology of the cell 19 (3), 1174-1184, 2008
LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice
HC Lee, T Inoue, J Sasaki, T Kubo, S Matsuda, Y Nakasaki, M Hattori, ...
Molecular biology of the cell 23 (24), 4689-4700, 2012
Impaired α-TTP-PIPs interaction underlies familial vitamin E deficiency
N Kono, U Ohto, T Hiramatsu, M Urabe, Y Uchida, Y Satow, H Arai
Science 340 (6136), 1106-1110, 2013
Structure of SARS-CoV-2 membrane protein essential for virus assembly
Z Zhang, N Nomura, Y Muramoto, T Ekimoto, T Uemura, K Liu, M Yui, ...
Nature communications 13 (1), 4399, 2022
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover
Y Tanaka, Y Shimanaka, A Caddeo, T Kubo, Y Mao, T Kubota, N Kubota, ...
Gut 70 (1), 180-193, 2021
Intracellular transport of fat‐soluble vitamins A and E
N Kono, H Arai
Traffic 16 (1), 19-34, 2015
Identification of genes and pathways involved in the synthesis of Mead acid (20: 3n− 9), an indicator of essential fatty acid deficiency
I Ichi, N Kono, Y Arita, S Haga, K Arisawa, M Yamano, M Nagase, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
Membrane lipid saturation activates IRE 1α without inducing clustering
Y Kitai, H Ariyama, N Kono, D Oikawa, T Iwawaki, H Arai
Genes to Cells 18 (9), 798-809, 2013
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo
N Kono, T Inoue, Y Yoshida, H Sato, T Matsusue, H Itabe, E Niki, J Aoki, ...
Journal of Biological Chemistry 283 (3), 1628-1636, 2008
Member of the membrane‐bound O‐acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity
S Matsuda, T Inoue, HC Lee, N Kono, F Tanaka, K Gengyo‐Ando, ...
Genes to Cells 13 (8), 879-888, 2008
Stearoyl-CoA desaturase 1 activity is required for autophagosome formation
Y Ogasawara, E Itakura, N Kono, N Mizushima, H Arai, A Nara, ...
Journal of Biological Chemistry 289 (34), 23938-23950, 2014
LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice
R Imae, T Inoue, Y Nakasaki, Y Uchida, Y Ohba, N Kono, H Nakanishi, ...
Journal of lipid research 53 (3), 335-347, 2012
Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation
Y Shimanaka, N Kono, Y Taketomi, M Arita, Y Okayama, Y Tanaka, ...
Nature medicine 23 (11), 1287-1297, 2017
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity
WJ Valentine, K Yanagida, H Kawana, N Kono, NN Noda, J Aoki, ...
Journal of Biological Chemistry 298 (1), 2022
Generic membrane-spanning features endow IRE1α with responsiveness to membrane aberrancy
N Kono, N Amin-Wetzel, D Ron
Molecular biology of the cell 28 (17), 2318-2332, 2017
Lysophosphatidylcholine export by human ABCA7
M Tomioka, Y Toda, NB Maņucat, H Akatsu, M Fukumoto, N Kono, H Arai, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017
Mitochondria‐type GPAT is required for mitochondrial fusion
Y Ohba, T Sakuragi, E Kage‐Nakadai, NH Tomioka, N Kono, R Imae, ...
The EMBO journal 32 (9), 1265-1279, 2013
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