Michael Maes
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Cytokines and major depression
OJG Schiepers, MC Wichers, M Maes
Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (2), 201-217, 2005
So depression is an inflammatory disease, but where does the inflammation come from?
M Berk, LJ Williams, FN Jacka, A O’Neil, JA Pasco, S Moylan, NB Allen, ...
BMC medicine 11 (1), 200, 2013
Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors
M Berk, F Kapczinski, AC Andreazza, OM Dean, F Giorlando, M Maes, ...
Neuroscience & biobehavioral reviews 35 (3), 804-817, 2011
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that illness
M Maes, P Galecki, YS Chang, M Berk
Progress in Neuro-Psychopharmacology and Biological Psychiatry 35 (3), 676-692, 2011
Evidence for an immune response in major depression: a review and hypothesis
M Maes
Progress in Neuro-Psychopharmacology and Biological Psychiatry 19 (1), 11-38, 1995
Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies
CA Köhler, TH Freitas, M Maes, NQ De Andrade, CS Liu, BS Fernandes, ...
Acta Psychiatrica Scandinavica 135 (5), 373-387, 2017
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
M Maes, R Yirmyia, J Noraberg, S Brene, J Hibbeln, G Perini, M Kubera, ...
Metabolic brain disease 24, 27-53, 2009
The serotonin hypothesis of major depression
M Maes
Psychopharmacology: The fourth generation of progress, 933-944, 1995
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and Th1-like response in stress-induced anxiety
M Maes, C Song, A Lin, R De Jongh, A Van Gastel, G Kenis, E Bosmans, ...
Cytokine 10 (4), 313-318, 1998
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the …
B Leonard, M Maes
Neuroscience & Biobehavioral Reviews 36 (2), 764-785, 2012
Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression
M Maes, E Bosmans, R De Jongh, G Kenis, E Vandoolaeghe, H Neels
Cytokine 9 (11), 853-858, 1997
Major depression and activation of the inflammatory response system
M Maes
Cytokines, stress, and depression, 25-46, 1999
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
M Maes, HY Meltzer, E Bosmans, R Bergmans, E Vandoolaeghe, ...
Journal of affective disorders 34 (4), 301-309, 1995
The new ‘5-HT’hypothesis of depression: cell-mediated immune activation induces indoleamine 2, 3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis …
M Maes, BE Leonard, AM Myint, M Kubera, R Verkerk
Progress in neuro-psychopharmacology and biological psychiatry 35 (3), 702-721, 2011
The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in …
M Mass, M Kubera, JC Leunis
Neuroendocrinology Letters 29 (1), 117-124, 2008
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
M Maes, M Berk, L Goehler, C Song, G Anderson, P Gałecki, B Leonard
BMC medicine 10, 1-19, 2012
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
M Maes
Progress in Neuro-Psychopharmacology and Biological Psychiatry 35 (3), 664-675, 2011
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy
L Capuron, A Ravaud, PJ Neveu, AH Miller, M Maes, R Dantzer
Molecular psychiatry 7 (5), 468-473, 2002
Lowered ω3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients
M Maes, A Christophe, J Delanghe, C Altamura, H Neels, HY Meltzer
Psychiatry research 85 (3), 275-291, 1999
The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications
S Moylan, M Maes, NR Wray, M Berk
Molecular psychiatry 18 (5), 595-606, 2013
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