Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions N Kanoh, S Kumashiro, S Simizu, Y Kondoh, S Hatakeyama, H Tashiro, ... Angewandte Chemie-International Edition 42 (45), 5584-5587, 2003 | 214 | 2003 |
Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics N Kanoh, K Honda, S Simizu, M Muroi, H Osada Angewandte Chemie-International Edition 44 (23), 3559-3562, 2005 | 151 | 2005 |
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I M Kawatani, H Okumura, K Honda, N Kanoh, M Muroi, N Dohmae, ... Proceedings of the National Academy of Sciences 105 (33), 11691-11696, 2008 | 150 | 2008 |
SPR imaging of photo-cross-linked small-molecule arrays on gold N Kanoh, M Kyo, K Inamori, A Ando, A Asami, A Nakao, H Osada Analytical chemistry 78 (7), 2226-2230, 2006 | 141 | 2006 |
The anticancer natural product pironetin selectively targets Lys352 of α-tubulin T Usui, H Watanabe, H Nakayama, Y Tada, N Kanoh, M Kondoh, T Asao, ... Chemistry & biology 11 (6), 799-806, 2004 | 133 | 2004 |
Tremorgenic indole alkaloids. The total synthesis of (−)-penitrem D AB Smith, N Kanoh, H Ishiyama, N Minakawa, JD Rainier, RA Hartz, ... Journal of the American Chemical Society 125 (27), 8228-8237, 2003 | 104 | 2003 |
Structure–activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof H Yamakoshi, H Ohori, C Kudo, A Sato, N Kanoh, C Ishioka, H Shibata, ... Bioorganic & medicinal chemistry 18 (3), 1083-1092, 2010 | 96 | 2010 |
Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts JT Woo, M Kawatani, M Kato, T Shinki, T Yonezawa, N Kanoh, ... Proceedings of the National Academy of Sciences 103 (12), 4729-4734, 2006 | 86 | 2006 |
Synthetic studies on daphnicyclidin A: enantiocontrolled construction of the BCD ring system S Ikeda, M Shibuya, N Kanoh, Y Iwabuchi Organic Letters 11 (8), 1833-1836, 2009 | 85 | 2009 |
Total synthesis of (−)-penitrem D AB Smith, N Kanoh, H Ishiyama, RA Hartz Journal of the American Chemical Society 122 (45), 11254-11255, 2000 | 85 | 2000 |
Photo‐Cross‐Linked Small‐Molecule Microarrays as Chemical Genomic Tools for Dissecting Protein–Ligand Interactions N Kanoh, A Asami, M Kawatani, K Honda, S Kumashiro, H Takayama, ... Chemistry–An Asian Journal 1 (6), 789-797, 2006 | 81 | 2006 |
Conversion of prelaureatin into laurallene, a bromo-allene compound, by enzymatic and chemical bromo-etherification reactions J Ishihara, Y Shimada, N Kanoh, Y Takasugi, A Fukuzawa, A Murai Tetrahedron 53 (25), 8371-8382, 1997 | 76 | 1997 |
Syntheses and Biological Evaluation of Irciniastatin A and the C1− C2 Alkyne Analogue T Watanabe, T Imaizumi, T Chinen, Y Nagumo, M Shibuya, T Usui, ... Organic letters 12 (5), 1040-1043, 2010 | 62 | 2010 |
An expedient route to a potent gastrin/CCK-B receptor antagonist (+)-AG-041R S Sato, M Shibuya, N Kanoh, Y Iwabuchi The Journal of Organic Chemistry 74 (19), 7522-7524, 2009 | 59 | 2009 |
Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells T Teruya, S Simizu, N Kanoh, H Osada FEBS letters 579 (11), 2463-2468, 2005 | 55 | 2005 |
Total synthesis of methyl sarcophytoate, a marine natural biscembranoid T Ichige, Y Okano, N Kanoh, M Nakata The Journal of Organic Chemistry 74 (1), 230-243, 2009 | 50 | 2009 |
Studies aimed at the total synthesis of Azadirachtin. A modeled connection of C-8 and C-14 in Azadirachtin T Fukuzaki, S Kobayashi, T Hibi, Y Ikuma, J Ishihara, N Kanoh, A Murai Organic letters 4 (17), 2877-2880, 2002 | 49 | 2002 |
Asymmetric total synthesis of (−)-scabronine G via intramolecular double Michael reaction and Prins cyclization N Kanoh, K Sakanishi, E Iimori, K Nishimura, Y Iwabuchi Organic Letters 13 (11), 2864-2867, 2011 | 46 | 2011 |
Eu(OTf)3-Catalyzed Highly Regioselective Nucleophilic Ring Opening of 2,3-Epoxy Alcohols: An Efficient Entry to 3-Substituted 1,2-Diol Derivatives S Uesugi, T Watanabe, T Imaizumi, M Shibuya, N Kanoh, Y Iwabuchi Organic letters 16 (17), 4408-4411, 2014 | 45 | 2014 |
Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-β-lactam core of chartellines S Sato, M Shibuya, N Kanoh, Y Iwabuchi Chemical Communications, 6264-6266, 2009 | 45 | 2009 |