フォロー
Rameshwar U. Kadam, Ph.D
Rameshwar U. Kadam, Ph.D
Senior Research Associate, The Scripps Research Institute
確認したメール アドレス: scripps.edu - ホームページ
タイトル
引用先
引用先
Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol
RU Kadam, IA Wilson
Proceedings of the National Academy of Sciences 114 (2), 206-214, 2017
4582017
Hepatitis C virus E2 envelope glycoprotein core structure
L Kong, E Giang, T Nieusma, RU Kadam, KE Cogburn, Y Hua, X Dai, ...
Science 342 (6162), 1090-1094, 2013
4382013
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB
EMV Johansson, SA Crusz, E Kolomiets, L Buts, RU Kadam, M Cacciarini, ...
Chemistry & biology 15 (12), 1249-1257, 2008
2782008
Design of protein-binding proteins from the target structure alone
L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ...
Nature 605 (7910), 551-560, 2022
2232022
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms
RU Kadam, M Bergmann, M Hurley, D Garg, M Cacciarini, MA Swiderska, ...
Angewandte Chemie (International ed. in English) 50 (45), 10631, 2011
1922011
Potent peptidic fusion inhibitors of influenza virus
RU Kadam, J Juraszek, B Brandenburg, C Buyck, WBG Schepens, ...
Science 358 (6362), 496-502, 2017
1522017
Recent trends in drug-likeness prediction: a comprehensive review of in silico methods
R Kadam, N Roy
Indian Journal of Pharmaceutical Sciences 69 (5), 609, 2007
1282007
CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
RU Kadam, D Garg, J Schwartz, R Visini, M Sattler, A Stocker, T Darbre, ...
ACS chemical biology 8 (9), 1925-1930, 2013
1152013
A small-molecule fusion inhibitor of influenza virus is orally active in mice
MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ...
Science 363 (6431), eaar6221, 2019
1142019
Glycopeptide Dendrimers with High Affinity for the Fucose‐Binding Lectin LecB from Pseudomonas aeruginosa
E Kolomiets, MA Swiderska, RU Kadam, EMV Johansson, KE Jaeger, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 562-569, 2009
982009
Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen
L Kong, DE Lee, RU Kadam, T Liu, E Giang, T Nieusma, F Garces, ...
Proceedings of the National Academy of Sciences 113 (45), 12768-12773, 2016
832016
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility
NC Wu, H Lv, AJ Thompson, DC Wu, WWS Ng, RU Kadam, CW Lin, ...
Cell host & microbe 25 (6), 836-844. e5, 2019
732019
Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin
ZVF Wright, NC Wu, RU Kadam, IA Wilson, DW Wolan
Bioorganic & medicinal chemistry letters 27 (16), 3744-3748, 2017
642017
Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids
E Johansson, RU Kadam
MedChemComm 2 (5), 418-420, 2011
642011
Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314–324 in complex with antibody IGH526
L Kong, RU Kadam, E Giang, TB Ruwona, T Nieusma, JC Culhane, ...
Journal of molecular biology 427 (16), 2617-2628, 2015
552015
Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini
M Stach, N Maillard, RU Kadam
MedChemComm 3 (1), 86-89, 2012
552012
Structure‐Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA
RU Kadam, M Bergmann, D Garg, G Gabrieli, A Stocker, T Darbre, ...
Chemistry–A European Journal 19 (50), 17054-17063, 2013
472013
A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin
RU Kadam, IA Wilson
Proceedings of the National Academy of Sciences 115 (16), 4240-4245, 2018
322018
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen
Y Yao, RU Kadam, CCD Lee, JL Woehl, NC Wu, X Zhu, S Kitamura, ...
Proceedings of the National Academy of Sciences 117 (31), 18431-18438, 2020
312020
Cluster analysis and two-dimensional quantitative structure–activity relationship (2D-QSAR) of Pseudomonas aeruginosa deacetylase LpxC inhibitors
RU Kadam, N Roy
Bioorganic & medicinal chemistry letters 16 (19), 5136-5143, 2006
272006
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