Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives M Humbert, C Guignabert, S Bonnet, P Dorfmüller, JR Klinger, MR Nicolls, ... European Respiratory Journal 53 (1), 2019 | 996 | 2019 |
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension M Rabinovitch, C Guignabert, M Humbert, MR Nicolls Circulation research 115 (1), 165-175, 2014 | 908 | 2014 |
Pulmonary arterial hypertension in patients treated by dasatinib D Montani, E Bergot, S Günther, L Savale, A Bergeron, A Bourdin, ... Circulation 125 (17), 2128-2137, 2012 | 753 | 2012 |
Relevant issues in the pathology and pathobiology of pulmonary hypertension RM Tuder, SL Archer, P Dorfmüller, SC Erzurum, C Guignabert, ... Journal of the American College of Cardiology 62 (25S), D4-D12, 2013 | 653 | 2013 |
Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)? A Huertas, D Montani, L Savale, J Pichon, L Tu, F Parent, C Guignabert, ... European Respiratory Journal 56 (1), 2020 | 405 | 2020 |
An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension G Hansmann, VA de Jesus Perez, TP Alastalo, CM Alvira, C Guignabert, ... The Journal of clinical investigation 118 (5), 1846-1857, 2008 | 397 | 2008 |
Right ventricular diastolic impairment in patients with pulmonary arterial hypertension S Rain, ML Handoko, P Trip, CTJ Gan, N Westerhof, GJ Stienen, ... Circulation 128 (18), 2016-2025, 2013 | 394 | 2013 |
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia S Eddahibi, C Guignabert, AM Barlier-Mur, L Dewachter, E Fadel, ... Circulation 113 (15), 1857-1864, 2006 | 385 | 2006 |
Dysregulated renin–angiotensin–aldosterone system contributes to pulmonary arterial hypertension FS de Man, L Tu, ML Handoko, S Rain, G Ruiter, C François, I Schalij, ... American journal of respiratory and critical care medicine 186 (8), 780-789, 2012 | 357 | 2012 |
Pulmonary arterial remodeling induced by a Th2 immune response E Daley, C Emson, C Guignabert, R de Waal Malefyt, J Louten, VP Kurup, ... The Journal of experimental medicine 205 (2), 361-372, 2008 | 308 | 2008 |
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats C Guignabert, B Raffestin, R Benferhat, W Raoul, P Zadigue, D Rideau, ... Circulation 111 (21), 2812-2819, 2005 | 284 | 2005 |
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension C Guignabert, C Phan, A Seferian, A Huertas, LY Tu, R Thuillet, C Sattler, ... The Journal of clinical investigation 126 (9), 3207-3218, 2016 | 256 | 2016 |
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents M Izikki, C Guignabert, E Fadel, M Humbert, L Tu, P Zadigue, P Dartevelle, ... The Journal of clinical investigation 119 (3), 512-523, 2009 | 249 | 2009 |
Targeted therapies in pulmonary arterial hypertension D Montani, MC Chaumais, C Guignabert, S Günther, B Girerd, X Jaïs, ... Pharmacology & therapeutics 141 (2), 172-191, 2014 | 246 | 2014 |
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension C Guignabert, M Izikki, LI Tu, Z Li, P Zadigue, AM Barlier-Mur, N Hanoun, ... Circulation research 98 (10), 1323-1330, 2006 | 231 | 2006 |
Pathogenesis of pulmonary arterial hypertension: lessons from cancer C Guignabert, L Tu, M Le Hiress, N Ricard, C Sattler, A Seferian, ... European Respiratory Review 22 (130), 543-551, 2013 | 224 | 2013 |
RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling C Guilluy, S Eddahibi, C Agard, C Guignabert, M Izikki, L Tu, L Savale, ... American journal of respiratory and critical care medicine 179 (12), 1151-1158, 2009 | 218 | 2009 |
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle–like cells in pulmonary hypertension N Ricard, L Tu, M Le Hiress, A Huertas, C Phan, R Thuillet, C Sattler, ... Circulation 129 (15), 1586-1597, 2014 | 202 | 2014 |
Proinflammatory signature of the dysfunctional endothelium in pulmonary hypertension. Role of the macrophage migration inhibitory factor/CD74 complex M Le Hiress, L Tu, N Ricard, C Phan, R Thuillet, E Fadel, P Dorfmüller, ... American journal of respiratory and critical care medicine 192 (8), 983-997, 2015 | 185 | 2015 |
New molecular targets of pulmonary vascular remodeling in pulmonary arterial hypertension: importance of endothelial communication C Guignabert, L Tu, B Girerd, N Ricard, A Huertas, D Montani, M Humbert Chest 147 (2), 529-537, 2015 | 176 | 2015 |