Adrian W Briggs
Adrian W Briggs
Chief Technology Officer, Shape Therapeutics
Verified email at - Homepage
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A draft sequence of the Neandertal genome
RE Green, J Krause, AW Briggs, T Maricic, U Stenzel, M Kircher, ...
science 328 (5979), 710-722, 2010
Genetic history of an archaic hominin group from Denisova Cave in Siberia
D Reich, RE Green, M Kircher, J Krause, N Patterson, EY Durand, B Viola, ...
Nature 468 (7327), 1053-1060, 2010
A high-coverage genome sequence from an archaic Denisovan individual
M Meyer, M Kircher, MT Gansauge, H Li, F Racimo, S Mallick, ...
Science 338 (6104), 222-226, 2012
Patterns of damage in genomic DNA sequences from a Neandertal
AW Briggs, U Stenzel, PLF Johnson, RE Green, J Kelso, K Prüfer, ...
Proceedings of the National Academy of Sciences 104 (37), 14616-14621, 2007
Analysis of one million base pairs of Neanderthal DNA
RE Green, J Krause, SE Ptak, AW Briggs, MT Ronan, JF Simons, L Du, ...
Nature 444 (7117), 330-336, 2006
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing
RE Green, AS Malaspinas, J Krause, AW Briggs, PLF Johnson, C Uhler, ...
Cell 134 (3), 416-426, 2008
Targeted retrieval and analysis of five Neandertal mtDNA genomes
AW Briggs, JM Good, RE Green, J Krause, T Maricic, U Stenzel, ...
Science 325 (5938), 318-321, 2009
Optimization of scarless human stem cell genome editing
L Yang, M Guell, S Byrne, JL Yang, A De Los Angeles, P Mali, J Aach, ...
Nucleic acids research 41 (19), 9049-9061, 2013
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
AW Briggs, U Stenzel, M Meyer, J Krause, M Kircher, S Pääbo
Nucleic acids research 38 (6), e87-e87, 2010
A complete mtDNA genome of an early modern human from Kostenki, Russia
J Krause, AW Briggs, M Kircher, T Maricic, N Zwyns, A Derevianko, ...
Current biology 20 (3), 231-236, 2010
Targeted investigation of the Neandertal genome by array-based sequence capture
HA Burbano, E Hodges, RE Green, AW Briggs, J Krause, M Meyer, ...
science 328 (5979), 723-725, 2010
Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary
J Krause, T Unger, A Noçon, AS Malaspinas, SO Kolokotronis, M Stiller, ...
BMC evolutionary biology 8, 1-12, 2008
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church
Nucleic acids research 40 (15), e117-e117, 2012
The Neandertal genome and ancient DNA authenticity
RE Green, AW Briggs, J Krause, K Prüfer, HA Burbano, M Siebauer, ...
The EMBO journal 28 (17), 2494-2502, 2009
Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers
SJ Spencer, MV Tamminen, SP Preheim, MT Guo, AW Briggs, IL Brito, ...
The ISME journal 10 (2), 427-436, 2016
Single cell bar-coding for antibody discovery
F Vigneault, AW BRIGGS
US Patent 9,816,088, 2017
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing
M Meyer, AW Briggs, T Maricic, B Höber, B Höffner, J Krause, ...
Nucleic Acids Research 36 (1), e5-e5, 2008
Hierarchical clustering can identify B cell clones with high confidence in Ig repertoire sequencing data
NT Gupta, KD Adams, AW Briggs, SC Timberlake, F Vigneault, ...
The Journal of Immunology 198 (6), 2489-2499, 2017
Methods of selecting T cell receptors using affinity oligonucleotide conjugates
F Vigneault, AW Briggs, SJ Goldfless, BJ Belmont
US Patent 10,393,743, 2019
Engineering and optimising deaminase fusions for genome editing
L Yang, AW Briggs, WL Chew, P Mali, M Guell, J Aach, DB Goodman, ...
Nature communications 7 (1), 13330, 2016
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