Novel role of PKR in inflammasome activation and HMGB1 release B Lu, T Nakamura, K Inouye, J Li, Y Tang, P Lundbäck, SI Valdes-Ferrer, ... Nature 488 (7413), 670-674, 2012 | 697 | 2012 |
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis T Nakamura, M Furuhashi, P Li, H Cao, G Tuncman, N Sonenberg, ... Cell 140 (3), 338-348, 2010 | 544 | 2010 |
Mice lacking a transcriptional corepressor Tob are predisposed to cancer Y Yoshida, T Nakamura, M Komoda, H Satoh, T Suzuki, JK Tsuzuku, ... Genes & development 17 (10), 1201-1206, 2003 | 158 | 2003 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation T Suzuki, K Junko, R Ajima, T Nakamura, Y Yoshida, T Yamamoto Genes & development 16 (11), 1356-1370, 2002 | 125 | 2002 |
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta T Nakamura, R Yao, T Ogawa, T Suzuki, C Ito, N Tsunekawa, K Inoue, ... Nature genetics 36 (5), 528-533, 2004 | 124 | 2004 |
Depletion of Mammalian CCR4b Deadenylase Triggers Elevation of the p27Kip1 mRNA Level and Impairs Cell Growth M Morita, T Suzuki, T Nakamura, K Yokoyama, T Miyasaka, T Yamamoto Molecular and cellular biology 27 (13), 4980-4990, 2007 | 121 | 2007 |
Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F‐Rb‐HDAC‐dependent and ‐independent pathways H Kimura, T Nakamura, T Ogawa, S Tanaka, K Shiota Nucleic acids research 31 (12), 3101-3113, 2003 | 113 | 2003 |
Potential role for snoRNAs in PKR activation during metabolic stress OA Youssef, SA Safran, T Nakamura, DA Nix, GS Hotamisligil, BL Bass Proceedings of the National Academy of Sciences 112 (16), 5023-5028, 2015 | 100 | 2015 |
Structural basis for the antiproliferative activity of the Tob-hCaf1 complex M Horiuchi, K Takeuchi, N Noda, N Muroya, T Suzuki, T Nakamura, ... Journal of biological chemistry 284 (19), 13244-13255, 2009 | 99 | 2009 |
Obesity resistance and increased hepatic expression of catabolism‐related mRNAs in Cnot3+/− mice M Morita, Y Oike, T Nagashima, T Kadomatsu, M Tabata, T Suzuki, ... The EMBO journal 30 (22), 4678-4691, 2011 | 80 | 2011 |
Small-molecule inhibitors of PKR improve glucose homeostasis in obese diabetic mice T Nakamura, A Arduini, B Baccaro, M Furuhashi, GS Hotamisligil Diabetes 63 (2), 526-534, 2014 | 69 | 2014 |
An FGF4-FRS2α-Cdx2 axis in trophoblast stem cells induces Bmp4 to regulate proper growth of early mouse embryos M Murohashi, T Nakamura, S Tanaka, T Ichise, N Yoshida, T Yamamoto, ... Stem Cells 28 (1), 113-121, 2010 | 62 | 2010 |
A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity T Nakamura, RC Kunz, C Zhang, T Kimura, CL Yuan, B Baccaro, ... Cell reports 11 (2), 295-307, 2015 | 53 | 2015 |
Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma M Yoneda, T Suzuki, T Nakamura, R Ajima, Y Yoshida, S Kakuta, K Sudo, ... Cancer science 100 (2), 225-232, 2009 | 49 | 2009 |
Azoospermia in mice with targeted disruption of the Brek/Lmtk2 (brain-enriched kinase/lemur tyrosine kinase 2) gene S Kawa, C Ito, Y Toyama, M Maekawa, T Tezuka, T Nakamura, ... Proceedings of the National Academy of Sciences 103 (51), 19344-19349, 2006 | 44 | 2006 |
Association of ANA, a member of the antiproliferative Tob family proteins, with a Cafl component of the CCR4 transcriptional regulatory complex Y Yoshida, E Hosoda, T Nakamura, T Yamamoto Japanese journal of cancer research 92 (6), 592-596, 2001 | 44 | 2001 |
Rapid and label-free isolation of small extracellular vesicles from biofluids utilizing a novel insulator based dielectrophoretic device L Shi, D Kuhnell, VJ Borra, SM Langevin, T Nakamura, L Esfandiari Lab on a Chip 19 (21), 3726-3734, 2019 | 38 | 2019 |
Cnot7‐null mice exhibit high bone mass phenotype and modulation of BMP actions K Washio‐Oikawa, T Nakamura, M Usui, M Yoneda, Y Ezura, I Ishikawa, ... Journal of Bone and Mineral Research 22 (8), 1217-1223, 2007 | 34 | 2007 |
Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology C Zhang, J Seo, K Murakami, ESB Salem, E Bernhard, VJ Borra, K Choi, ... Nature communications 9 (1), 1-15, 2018 | 31 | 2018 |
Adaptive thermogenesis in mice is enhanced by opsin 3-dependent adipocyte light sensing G Nayak, KX Zhang, S Vemaraju, Y Odaka, ED Buhr, A Holt-Jones, ... Cell reports 30 (3), 672-686. e8, 2020 | 30 | 2020 |