Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 EM Valente, PM Abou-Sleiman, V Caputo, MMK Muqit, K Harvey, ... Science 304 (5674), 1158-1160, 2004 | 4225 | 2004 |
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study DG Healy, M Falchi, SS O'Sullivan, V Bonifati, A Durr, S Bressman, ... The Lancet Neurology 7 (7), 583-590, 2008 | 1695 | 2008 |
Expanding insights of mitochondrial dysfunction in Parkinson's disease PM Abou-Sleiman, MMK Muqit, NW Wood Nature Reviews Neuroscience 7 (3), 207-219, 2006 | 1119 | 2006 |
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia SE Browne, AC Bowling, U Macgarvey, MJ Baik, SC Berger, MMK Muquit, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 1087 | 1997 |
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ... Open biology 2 (5), 120080, 2012 | 954 | 2012 |
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 A Kazlauskaite, C Kondapalli, R Gourlay, DG Campbell, MS Ritorto, ... Biochemical Journal 460 (1), 127-141, 2014 | 833 | 2014 |
Inhibition of neuronal nitric oxide synthase by 7‐nitroindazole protects against MPTP‐induced neurotoxicity in mice JB Schulz, RT Matthews, MMK Muqit, SE Browne, MF Beal Journal of neurochemistry 64 (2), 936-939, 1995 | 539 | 1995 |
Basal mitophagy occurs independently of PINK1 in mouse tissues of high metabolic demand TG McWilliams, AR Prescott, L Montava-Garriga, G Ball, F Singh, E Barini, ... Cell metabolism 27 (2), 439-449. e5, 2018 | 527 | 2018 |
mito-QC illuminates mitophagy and mitochondrial architecture in vivo TG McWilliams, AR Prescott, GFG Allen, J Tamjar, MJ Munson, ... Journal of Cell Biology 214 (3), 333-345, 2016 | 463 | 2016 |
PINK1 protein in normal human brain and Parkinson's disease S Gandhi, MMK Muqit, L Stanyer, DG Healy, PM Abou-Sleiman, ... Brain 129 (7), 1720-1731, 2006 | 420 | 2006 |
PINK1 and Parkin: emerging themes in mitochondrial homeostasis TG McWilliams, MMK Muqit Current opinion in cell biology 45, 83-91, 2017 | 311 | 2017 |
Modelling neurodegenerative diseases in Drosophila: a fruitful approach? MMK Muqit, MB Feany Nature Reviews Neuroscience 3 (3), 237-243, 2002 | 256 | 2002 |
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog DT Rogerson, A Sachdeva, K Wang, T Haq, A Kazlauskaite, SM Hancock, ... Nature chemical biology 11 (7), 496-503, 2015 | 248 | 2015 |
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK 1‐dependent phosphorylation and activation A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ... EMBO reports 16 (8), 939-954, 2015 | 239 | 2015 |
A heterozygous effect for PINK1 mutations in Parkinson's disease? PM Abou‐Sleiman, MMK Muqit, NQ McDonald, YX Yang, S Gandhi, ... Annals of neurology 60 (4), 414-419, 2006 | 209 | 2006 |
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress MMK Muqit, PM Abou‐Sleiman, AT Saurin, K Harvey, S Gandhi, E Deas, ... Journal of neurochemistry 98 (1), 156-169, 2006 | 200 | 2006 |
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ... The EMBO journal 34 (22), 2840-2861, 2015 | 189 | 2015 |
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ... Open biology 4 (3), 130213, 2014 | 153 | 2014 |
UCHL‐1 is not a Parkinson's disease susceptibility gene DG Healy, PM Abou‐Sleiman, JP Casas, KR Ahmadi, T Lynch, S Gandhi, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 144 | 2006 |
PINK1 (PARK6) associated Parkinson disease in Ireland DG Healy, PM Abou-Sleiman, JM Gibson, OA Ross, S Jain, S Gandhi, ... Neurology 63 (8), 1486-1488, 2004 | 137 | 2004 |