Keiko Nakayama
Keiko Nakayama
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Mice Lacking p27Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors
K Nakayama, N Ishida, M Shirane, A Inomata, T Inoue, N Shishido, I Horii, ...
Cell 85 (5), 707-720, 1996
Ubiquitin ligases: cell-cycle control and cancer
KI Nakayama, K Nakayama
Nature Reviews Cancer 6 (5), 369-381, 2006
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
K Miyamoto, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, ...
Cell stem cell 1 (1), 101-112, 2007
Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication
K Nakayama, H Nagahama, YA Minamishima, M Matsumoto, I Nakamichi, ...
The EMBO journal 19 (9), 2069-2081, 2000
Phosphorylation‐dependent degradation of c‐Myc is mediated by the F‐box protein Fbw7
M Yada, S Hatakeyama, T Kamura, M Nishiyama, R Tsunematsu, H Imaki, ...
The EMBO journal 23 (10), 2116-2125, 2004
An F‐box protein, FWD1, mediates ubiquitin‐dependent proteolysis of β‐catenin
M Kitagawa, S Hatakeyama, M Shirane, M Matsumoto, N Ishida, K Hattori, ...
The EMBO journal 18 (9), 2401-2410, 1999
Essential role for ZAP-70 in both positive and negative selection of thymocytes
I Negishi, N Motoyama, K Nakayama, K Nakayama, S Senju, ...
Nature 376 (6539), 435-438, 1995
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
EH Kobayashi, T Suzuki, R Funayama, T Nagashima, M Hayashi, ...
Nature communications 7 (1), 1-14, 2016
Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− mice
H Takai, K Tominaga, N Motoyama, YA Minamishima, H Nagahama, ...
Genes & development 14 (12), 1439-1447, 2000
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
G Bornstein, J Bloom, D Sitry-Shevah, K Nakayama, M Pagano, ...
Journal of Biological Chemistry 278 (28), 25752-25757, 2003
The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
N Von Der Lehr, S Johansson, S Wu, F Bahram, A Castell, C Cetinkaya, ...
Molecular cell 11 (5), 1189-1200, 2003
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
K Nakayama, I Negishi, K Kuida, H Sawa, DY Loh
Proceedings of the National Academy of Sciences 91 (9), 3700-3704, 1994
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
K Nakayama, I Negishi, K Kuida, Y Shinkai, MC Louie, LE Fields, ...
Science 261 (5128), 1584-1588, 1993
Mitogenic signalling and the p16 INK4a–Rb pathway cooperate to enforce irreversible cellular senescence
A Takahashi, N Ohtani, K Yamakoshi, S Iida, H Tahara, K Nakayama, ...
Nature cell biology 8 (11), 1291-1297, 2006
Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ
A Miyamoto, K Nakayama, H Imaki, S Hirose, Y Jiang, M Abe, ...
Nature 416 (6883), 865-869, 2002
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27 Kip1 at G1 phase
T Kamura, T Hara, M Matsumoto, N Ishida, F Okumura, S Hatakeyama, ...
Nature cell biology 6 (12), 1229-1235, 2004
Regulation of the cell cycle by SCF-type ubiquitin ligases
KI Nakayama, K Nakayama
Seminars in cell & developmental biology 16 (3), 323-333, 2005
Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis
H Nishitani, N Sugimoto, V Roukos, Y Nakanishi, M Saijo, C Obuse, ...
The EMBO journal 25 (5), 1126-1136, 2006
Skp2-mediated degradation of p27 regulates progression into mitosis
K Nakayama, H Nagahama, YA Minamishima, S Miyake, N Ishida, ...
Developmental cell 6 (5), 661-672, 2004
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
T Furuyama, K Kitayama, Y Shimoda, M Ogawa, K Sone, K Yoshida-Araki, ...
Journal of Biological Chemistry 279 (33), 34741-34749, 2004
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