| NAD+ metabolism and its roles in cellular processes during ageing AJ Covarrubias, R Perrone, A Grozio, E Verdin Nature reviews Molecular cell biology 22 (2), 119-141, 2021 | 738 | 2021 |
| The TSC-mTOR pathway regulates macrophage polarization V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ... Nature communications 4 (1), 2834, 2013 | 570 | 2013 |
| Ketogenic diet reduces midlife mortality and improves memory in aging mice JC Newman, AJ Covarrubias, M Zhao, X Yu, P Gut, CP Ng, Y Huang, ... Cell metabolism 26 (3), 547-557. e8, 2017 | 414 | 2017 |
| Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ... elife 5, e11612, 2016 | 365 | 2016 |
| Control of macrophage metabolism and activation by mTOR and Akt signaling AJ Covarrubias, HI Aksoylar, T Horng Seminars in immunology 27 (4), 286-296, 2015 | 350 | 2015 |
| SARS-CoV-2, COVID-19 and the aging immune system JM Bartleson, D Radenkovic, AJ Covarrubias, D Furman, DA Winer, ... Nature aging 1 (9), 769-782, 2021 | 264 | 2021 |
| Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Nature metabolism 2 (11), 1265-1283, 2020 | 240 | 2020 |
| Toll-like receptor 3–mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance AI Chin, AK Miyahira, A Covarrubias, J Teague, B Guo, PW Dempsey, ... Cancer research 70 (7), 2595-2603, 2010 | 130 | 2010 |
| ROS sets the stage for macrophage differentiation A Covarrubias, V Byles, T Horng Cell research 23 (8), 984-985, 2013 | 108 | 2013 |
| IL-6 strikes a balance in metabolic inflammation AJ Covarrubias, T Horng Cell metabolism 19 (6), 898-899, 2014 | 60 | 2014 |
| Nuclear morphology is a deep learning biomarker of cellular senescence I Heckenbach, GV Mkrtchyan, MB Ezra, D Bakula, JS Madsen, ... Nature Aging 2 (8), 742-755, 2022 | 57 | 2022 |
| The TSC-mTOR pathway regulates macrophage polarization. Nat Commun 4: 2834 V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ... | 20 | 2013 |
| The intestinal immune system and gut barrier function in obesity and ageing SJ Shemtov, R Emani, O Bielska, AJ Covarrubias, E Verdin, JK Andersen, ... The FEBS Journal 290 (17), 4163-4186, 2023 | 17 | 2023 |
| Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Biorxiv, 609438, 2019 | 13 | 2019 |
| Senescent cells promote tissue NAD (+) decline during ageing via the activation of CD38 (+) macrophages (vol 2, pg 1265, 2020) AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... NATURE METABOLISM 3 (1), 120-121, 2021 | | 2021 |
| Aging-related inflammation driven by cellular senescence enhances NAD AJ Covarrubias, JA Lopez-Dominguez, R Perrone Trends Biochem Sci 32, 12-19, 2018 | | 2018 |
| THE ROLE OF MACROPHAGES IN NAD+ HOMEOSTASIS DURING AGING AJ Covarrubias, EM Verdin Innovation in Aging 1 (Suppl 1), 1205, 2017 | | 2017 |
| The Role of Nutrient Sensing in Macrophage Polarization AJ Covarrubias | | 2016 |
| SUPPRESSION OF PROSTATE CANCER GROWTH WITH ACTIVATION OF TOLL-LIKE RECEPTOR 3 AI Chin, A Miyahara, A Covarrubias, PW Dempsey, G Cheng The Journal of Urology 181 (4S), 186-186, 2009 | | 2009 |
