| Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model Y Yoshiyama, M Higuchi, B Zhang, SM Huang, N Iwata, TC Saido, ... Neuron 53 (3), 337-351, 2007 | 2103 | 2007 |
| Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial JR Sims, JA Zimmer, CD Evans, M Lu, P Ardayfio, JD Sparks, AM Wessels, ... Jama 330 (6), 512-527, 2023 | 402 | 2023 |
| Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy B Zhang, M Higuchi, Y Yoshiyama, T Ishihara, MS Forman, D Martinez, ... Journal of Neuroscience 24 (19), 4657-4667, 2004 | 216 | 2004 |
| Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies M Ono, N Sahara, K Kumata, B Ji, R Ni, S Koga, DW Dickson, ... Brain 140 (3), 764-780, 2017 | 214 | 2017 |
| Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice T Ishihara, B Zhang, M Higuchi, Y Yoshiyama, JQ Trojanowski, VMY Lee The American journal of pathology 158 (2), 555-562, 2001 | 211 | 2001 |
| Therapeutic strategies for tau mediated neurodegeneration Y Yoshiyama, VMY Lee, JQ Trojanowski Journal of Neurology, Neurosurgery & Psychiatry 84 (7), 784-795, 2013 | 176 | 2013 |
| Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brain. M Asahina, Y Yoshiyama, T Hattori Clinical neuropathology 20 (2), 60-63, 2001 | 171 | 2001 |
| Apoptosis related antigen, LeY and nick-end labeling are positive in spinal motor neurons in amyotrophic lateral sclerosis Y Yoshiyama, T Yamada, K Asanuma, T Asahi Acta neuropathologica 88, 207-211, 1994 | 158 | 1994 |
| Enhanced neurofibrillary tangle formation, cerebral atrophy, and cognitive deficits induced by repetitive mild brain injury in a transgenic tauopathy mouse model Y Yoshiyama, K Uryu, M Higuchi, L Longhi, R Hoover, S Fujimoto, ... Journal of neurotrauma 22 (10), 1134-1141, 2005 | 146 | 2005 |
| Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer’s disease brain Y Yoshiyama, M Asahina, T Hattori Acta neuropathologica 99, 91-95, 2000 | 143 | 2000 |
| Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies M Higuchi, B Zhang, MS Forman, Y Yoshiyama, JQ Trojanowski, VMY Lee Journal of neuroscience 25 (41), 9434-9443, 2005 | 140 | 2005 |
| Neuromyelitis optica and anti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay S Hayakawa, M Mori, A Okuta, A Kamegawa, Y Fujiyoshi, Y Yoshiyama, ... Journal of neuroimmunology 196 (1-2), 181-187, 2008 | 135 | 2008 |
| Anti-inflammatory action of donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model Y Yoshiyama, A Kojima, C Ishikawa, K Arai Journal of Alzheimer's Disease 22 (1), 295-306, 2010 | 130 | 2010 |
| Serum levels of tumor necrosis factor–α in chronic inflammatory demyelinating polyneuropathy S Misawa, S Kuwabara, M Mori, N Kawaguchi, Y Yoshiyama, T Hattori Neurology 56 (5), 666-669, 2001 | 110 | 2001 |
| Clinical study of FK506 in patients with myasthenia gravis T Konishi, Y Yoshiyama, M Takamori, K Yagi, E Mukai, T Saida, ... Muscle & nerve 28 (5), 570-574, 2003 | 102 | 2003 |
| White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues T Yamada, Y Yoshiyama, H Sato, M Seiki, A Shinagawa, M Takahashi Acta neuropathologica 90, 421-424, 1995 | 96 | 1995 |
| Long-term treatment of generalised myasthenia gravis with FK506 (tacrolimus) T Konishi, Y Yoshiyama, M Takamori, T Saida Journal of Neurology, Neurosurgery & Psychiatry 76 (3), 448-450, 2005 | 95 | 2005 |
| Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes Y Yoshiyama, B Zhang, J Bruce, JQ Trojanowski, VMY Lee Journal of Neuroscience 23 (33), 10662-10671, 2003 | 94 | 2003 |
| Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments T Ishihara, M Higuchi, B Zhang, Y Yoshiyama, M Hong, JQ Trojanowski, ... Journal of Neuroscience 21 (16), 6026-6035, 2001 | 88 | 2001 |
| Markedly reduced axonal potassium channel expression in human sporadic amyotrophic lateral sclerosis: an immunohistochemical study K Shibuya, S Misawa, K Arai, M Nakata, K Kanai, Y Yoshiyama, K Ito, ... Experimental neurology 232 (2), 149-153, 2011 | 69 | 2011 |
Shunsuke KogaHospital of the University of Pennsylvania確認したメール アドレス: pennmedicine.upenn.edu
